Quality of life and clinical characterization of patients with vernal keratoconjunctivitis in a pediatric population in Colombia

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Quality of life and clinical characterization of patients with vernal keratoconjunctivitis in a pediatric population in Colombia
C.M. Gómez-Henaoa,b, C.I. Herrera-Moralesa,c, R. Ramírez-Giraldoa,d, R. Cardona-Villaa,b,∗

a GACE Group Research Associate, Universidad de Antioquia, Colombia
b Clinical Allergist IPS Universitaria - Universidad de Antioquia, Colombia
c Clinical Allergist, Hospital Universitario San Vicente Fundación, Colombia d Pediatric Allergist, IPS Universitaria - Universidad de Antioquia, Colombia




Abstract Vernal keratoconjunctivitis is one of the most serious ocular allergies that have the potential to induce large ocular morbidity and significant visual changes affecting the quality of life of these individuals.

Methodology: This study was conducted in two phases. The first phase consisted of the clinical characterization of 32 patients from the Clinical Allergology center of the I.P.S. Universitaria from July 2014 to February 2015. A retrospective analysis of medical records was performed.


In the second phase, the evaluation of quality of life was conducted using the questionnaire KIDSCREEN 27, which was validated in our population and evaluated as recommended by the creators of this instrument.

Results: A total of 24 patients (75%) were men, mean age of 12.1 (SD 2.6) years. 100% of the patients had clinical evaluation and were monitored by Allergology and Ophthalmology, 12 patients (37.5%) were found in mild level, 5 patients (15.6%) were moderate and 14 patients (43.8%) were severe level. The most common symptoms were pruritus (75%), photophobia (50%), lacrimation (37.5%), and secretions (28.1%). 65.6% had a family history of atopy and 84.4% had an allergic comorbidity. Aeroallergen skin tests were found positive in 25 patients (78.1%). All patients had initiated ocular treatment by the time the survey of quality of life was conducted; but, they still had low quality of life scores in the 5 domains assessed. When the scores were evaluated by gender, the only statistically significant difference was found in the domain of family life and free time, which was lower for women.


Conclusion: The vernal keratoconjunctivitis is a disease more prevalent in men. It apparently has an important atopic base in our environment, which due to its severe ocular involvement causes a marked decrease in the quality of life of the children who present it.



∗ Corresponding author.
E-mail address: rcv2016udea@gmail.com (R. Cardona-Villa). 





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