ALERGOLOGÍA PARA MÉDICOS Y PACIENTES 2021

 

Predictors of severe anaphylaxis in Hymenoptera venom allergy The importance of absence of urticaria and angioedema Authors: Maria Chapsa, MD Henriette Roensch, MSScMathias Langner, MScStefan Beissert, MDAndrea Bauer, MD Abstract Background Severe anaphylaxis (SA) in Hymenoptera venom allergy has been associated with a number of risk factors. However, the effect of several of those risk factors on the severity of anaphylaxis is poorly defined. Objective To evaluate risk factors for SA in Hymenoptera venom allergy. Methods We evaluated data from 500 patients who were referred to our department for the diagnosis of Hymenoptera venom allergy during a period of 11 years to identify risk factors for SA. Results Six significant risk factors for SA were identified ( P < .05): short interval from sting to reaction, absence of urticaria or angioedema (U/A) during anaphylaxis, older age, male sex, elevation of baseline serum tryptase (BST) level, and diagnosis of systemic mastocytosis. Moreov

 Spanish Guidelines for Diagnosis, Management, Treatment, and Prevention of DRESS Syndrome Authors: R Cabañas 1 2 3 4, E Ramírez 2 3 5, E Sendagorta 3 6, R Alamar 7, R Barranco 3 8 9, N Blanca-López 10, I Doña 11 12, J Fernández 13, I Garcia-Nunez 14, J García-Samaniego 15, R Lopez-Rico 16, E Marín-Serrano 17, C Mérida 18, M Moya 19, N R Ortega-Rodríguez 20, B Rivas Becerra 2 21, P Rojas-Perez-Ezquerra 3 22, M J Sánchez-González 3 23, C Vega-Cabrera 2 21, C Vila-Albelda 24, T Bellón 2 3 25 Abstract Background and objective: Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a complex multisystemic severe drug hypersensitivity reaction whose diagnosis and management are troublesome. DRESS syndrome requires management by various specialists. The correct identification of the culprit drug is essential to ensure safe future therapeutic options for the patient. There are no previous Spanish guidelines or consensus statements on DRESS syndrome. Objective: To draft a re