ALERGOLOGÍA PARA MÉDICOS Y PACIENTES 2021

Anaphylaxis-a 2020 Practice Parameter Update, Systematic Review, and Grading of Recommendations, Assessment, Development and Evaluation (GRADE) Analysis Authors: Marcus S Shaker 1, Dana V Wallace 2, David B K Golden 3, John Oppenheimer 4, Jonathan A Bernstein 5, Ronna L Campbell 6, Chitra Dinakar 7, Anne Ellis 8, Matthew Greenhawt 9, David A Khan 10, David M Lang 11, Eddy S Lang 12, Jay A Lieberman 13, Jay Portnoy 14, Matthew A Rank 15, David R Stukus 16, Julie Wang 17, Collaborators; Natalie Riblet 18, Aiyana M P Bobrownicki 18, Teresa Bontrager 19, Jarrod Dusin 19, Jennifer Foley 19, Becky Frederick 19, Eyitemi Fregene 18, Sage Hellerstedt 18, Ferdaus Hassan 19, Kori Hess 19, Caroline Horner 20, Kelly Huntington 19, Poojita Kasireddy 18, David Keeler 19, Bertha Kim 18, Phil Lieberman 13, Erin Lindhorst 19, Fiona McEnany 18, Jennifer Milbank 18, Helen Murphy 19, Oriana Pando 18, Ami K Patel 18, Nicole Ratliff 19, Robert Rhodes 19, Kim Robertson 19, Hope Scott 19, Audrey Snell 19, ...

Pruebas de función pulmonar (Dra. Catalina López Ceballos)

Inmunomoduladores en infecciones respiratorias recurrentes (Dra. Ana María Calle)

Alergia a epitelios (Dr. Jaime Sosa Moreno)

Fisiopatología de la dermatitis de contacto (Dr. Steven Fuentes Abreu)

Fisiopatología de la urticaria crónica espontánea (Dra Gloria Gil) Generalidades de la rinitis alérgica local (Dr Luis Santamaría)

Fisiopatología de la dermatitis atópica por el Dr. Steven Abreu Seguridad de los inhibidores de la calcineurina tópicos por la Dra. Susana Uribe

Fisiopatología del asma Dra. Catalina López (Diciembre de 2018)

Pruebas de exposición controlada Dra. Ana María Calle (Noviembre de 2018)

Fisiopatología de las reacciones de hipersensibilidad Dra. Gloria Gil (Octubre de 2018).

Anxiety and Depression Effects During Drug Provocation Test. Authors: Losappio LM, Cappai A, Arcolaci A, Badiu I, Bonadonna P, Boni E, Bussolino C, Caminati M, Galati P, Heffler E, Intravaia R, Mauro M, Massaro I, Romano A, Rumi G, Parolo A, Pizzimenti S, Nichelatti M, Pastorello EA. Abstract: BACKGROUND: Drug provocation test (DPT) represents the gold standard for the diagnosis of drug allergy. A DPT can be performed in a single-blind placebo-controlled manner. In anxiety and depressive disorders, patients need to be evaluated to understand the nature of placebo reactions. OBJECTIVE: The aim of this study was to evaluate the psychological profile of patients with reactions to placebo during a DPT. METHODS: We consecutively enrolled patients with suspected drug allergy undergoing a DPT preceded by the administration of the placebo. All patients underwent the Hospital Anxiety and Depression Scale (HADS), a questionnaire aimed to identify anxiety and depression, before ...

Next generation anti-S. aureus vaccines: a potential new therapeutic option for atopic dermatitis? Authors:  Clowry J , Pediatric Dermatology, Our Lady's Children's Hospital Crumlin, Dublin 12, Ireland; National Children's Research Centre, Our Lady's Children's Hospital Crumlin, Dublin 12, Ireland; Clinical Medicine, Trinity College Dublin, Dublin 2, Ireland. Irvine AD , Pediatric Dermatology, Our Lady's Children's Hospital Crumlin, Dublin 12, Ireland; National Children's Research Centre, Our Lady's Children's Hospital Crumlin, Dublin 12, Ireland; Clinical Medicine, Trinity College Dublin, Dublin 2, Ireland. McLoughlin RM , Host-Pathogen Interactions Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Dublin 2, Ireland. Abstract:  Disease severity in patients with atopic dermatitis (AD) is directly correlated with colonization by Staphylococcus aureus.1 An increasing body of evidence now also supp...

Roles of MAS-related G protein coupled receptor-X2 (MRGPRX2) on mast cell-mediated host defense, pseudoallergic drug reactions and chronic inflammatory diseases. Authors: Hariharan Subramanian, PhD,  Kshitij Gupta, PhD, Hydar Ali, PhD ; Department of Pathology, University of Pennsylvania School of Dental Medicine, Philadelphia. Abstract:  Mast cells (MCs), which are granulated tissue-resident cells of hematopoietic lineage, contribute to vascular homeostasis, innate/adaptive immunity, and wound healing. However, MCs are best known for their roles in allergic and inflammatory diseases, such as anaphylaxis, food allergy, rhinitis, itch, urticaria, atopic dermatitis, and asthma. In addition to the high-affinity IgE receptor (FcεRI), MCs express numerous G protein-coupled receptors (GPCRs), which are the largest group of membrane receptor proteins and the most common targets of drug therapy. Antimicrobial host defense peptides, neuropeptides, major basic protein, e...

Allergic Contact Dermatitis. Authors:  Kostner L 1, Anzengruber F 1, Guillod C 1, Recher M 2, Schmid-Grendelmeier P 1, Navarini AA 3. Author information: 1 Department of Dermatology, University Hospital Zurich, Gloriastrasse 31, 8091, Zurich, Switzerland. 2 Immunodeficiency Clinic, Medical Outpatient Unit and Immunodeficiency Lab, Department Biomedicine, University Hospital, Petersgraben 4, 4031, Basel, Switzerland. 3 Department of Dermatology, University Hospital Zurich, Gloriastrasse 31, 8091, Zurich, Switzerland. Electronic address: alexander.navarini@usz.ch. Abstract:  Allergic contact dermatitis (ACD) is a common skin disease caused by a T cell-mediated immune reaction to usually innocuous allergens. ACD can have grave medical and socioeconomic consequences. ACD and irritant contact dermatitis often occur together. A detailed history and clinical examination are crucial and guide patch testing, which is the gold standard to diagnose ACD. T-cell clones per...

Hipersensibilidad a sulfonamidas Presentación realizada por la Dra. Susana Uribe durante la jornada académica del jueves 6 de septiembre de 2018:

Sulfonamide Drug Allergy  Joshua M. Dorn1 & Mollie Alpern1 & Caitlin McNulty1 & Gerald W. Volcheck1 Abstract: Purpose of Review We sought to review past and current literature on sulfonamide drug allergy and distill it in a practical manner to assist the clinician, specifically focusing on cross-reactivity and desensitization. Recent Findings There do not appear to be consistent genetic markers to reliably predict features of or the presence hypersensitivity reactions. Recent evidence continues to alleviate early concerns cross-reactivity between sulfonamide antibiotics and nonantibiotics. Summary Sulfonamide drug allergy is frequently encountered by the practicing clinician. For sulfonamide antibiotics, delayed rash is the most common clinical manifestation. There is no current evidence to support avoidance of all non-antibiotic sulfonamides in those with a reported allergy to sulfonamide antibiotics, although certain scenarios require caution. Available evid...

JORNADA ACADÉMICA Dra Paola Marín Residente de otorrinolaringología de primer año quien rota actualmente en el servicio de alergología clínica.  Tema: Enfermedad respiratoria exacerbada por AINEs

JORNADA ACADÉMICA 23/08/2018 El día de mañana la discusión será centrada en el tema de lubricantes oculares, el artículo recomendado es el siguiente: Ocular surface lubricants Autores:  Leonard Bielory,  Thomas Jefferson University, Philadelphia, PA; Rutgers University Center for Environmental Prediction, New Brunswick; University Asthma and Allergy Associates, Springfield, NJ, USA. Preeti Wagle,  University Asthma and Allergy Associates, Springfield, NJ, USA. Abstract: Purpose of review: The purpose of this article is to provide an overview of the ocular lubricants currently available, consider the components of the various formulations and highlight the status of preservative use in the treatment of anterior ocular surface diseases. Recent findings The primary components of ocular surface lubrication have been, in the past, based on various cellulose formulations that increase hydration. Advances in lubrication have come from are...

JORNADA ACADEMICA 23 de agosto de 2018 El día 23 de agosto 2018 se realizara jornada académica, en donde se revisara el tema hipersensibilidad a AINEs. El seminario estará disponible a partir de mañana en la plataforma de teleducación de la pagina de la Universidad de Antioquia, el link estará disponible a partir de mañana.  Articulo recomendado:   NSAIDs hypersensitivity: questions not resolved PUNTOS CLAVE POR AUTORES -La hipersensibilidad a los AINEs incluye una amplia variedad de entidades clínicas inducidas por mecanismos inmunológicos específicos (IgE o células T), así como mecanismos basados ​​en anomalías en las vías bioquímicas relacionadas con el metabolismo de leucotrienos-prostaglandinas. -La piel es el órgano más frecuente involucrado, independientemente de los mecanismos subyacentes. -Las pruebas cutáneas para reacciones IgE y respuesta dependiente de células T tienen un valor limitado. -Para las reacciones intolerant...

JORNADA ACADÉMICA 16.08.18 El día de hoy se realizó jornada académica con las siguientes presentaciones: 1. Angioedema Hereditario a cargo de la Dra. Karent Betancur. Diapositivas disponibles en el siguiente enlace  https://drive.google.com/open?id=1cCH-RDnZLSBWHNXS8QgzDrZZjS4kcb7c 2. Tratamiento de alergia ocular a cargo del Dr. Luis Carlos Santamaría. Presentación disponible en el siguiente enlace: https://www.youtube.com/watch?v=Pe6rJXcSKew&list=PLWutZMaMUREeyppOkA_BSZWFI5rlEgM8e&index=24