ALERGOLOGÍA PARA MÉDICOS Y PACIENTES 2021

Phenotypes and endotypes of food allergy: A path to better understanding the pathogenesis and prognosis of food allergy. Authors: Baker MG1, Sampson HA2. Author information 1Division of Allergy and Immunology, Department of Pediatrics, Elliot and Roslyn Jaffe Food Allergy Institute, Icahn School of Medicine at Mount Sinai, New York, New York. 2Division of Allergy and Immunology, Department of Pediatrics, Elliot and Roslyn Jaffe Food Allergy Institute, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address: hugh.sampson@mssm.edu.  DOI:   10.1016/j.anai.2018.01.027

Facial Dermatitis in Male Patients Referred for Patch Testing: Retrospective Analysis of North American Contact Dermatitis Group Data, 1994 to 2016. Authors: Warshaw EM1,2, Schlarbaum JP1,3, Maibach HI4, Silverberg JI5, Taylor JS6, Atwater AR7, Reeder MJ8, DeKoven JG9, Pratt MD10, DeLeo VA11, Zug KA12, Fransway AF13, Belsito DV14, Mathias T15, Fowler JF Jr16, Marks JG Jr17, Sasseville D18, Zirwas MJ19. Author information 1Department of Dermatology, Minneapolis Veterans Affairs Medical Center, Minneapolis, Minnesota. 2Department of Dermatology, University of Minnesota, Minneapolis. 3University of Minnesota Medical School, Minneapolis. 4Department of Dermatology, University of California, San Francisco. 5Department of Dermatology, The George Washington University, Washington, DC. 6Department of Dermatology, Cleveland Clinic, Cleveland, Ohio. 7Department of Dermatology, Duke University, Durham, North Carolina. 8Department of Dermatology, University of Wisconsin Medical Sch

Sulfonamide Hypersensitivity: Fact and Fiction. Authors: Khan DA1, Knowles SR2, Shear NH3. Author information 1 Division of Allergy and Immunology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Tex. Electronic address: dave.khan@utsouthwestern.edu. 2 Division of Clinical Pharmacology and Toxicology, Department of Pharmacy, University of Toronto, Toronto, Ontario, Canada. 3 Department of Dermatology, University of Toronto, Toronto, Ontario, Canada; Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada. Abstract Sulfonamide antimicrobials are commonly reported as causing drug allergy and have been implicated in a variety of hypersensitivity reactions including immediate IgE-mediated reactions, benign T-cell-mediated rashes, and severe cutaneous adverse reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic symptoms. Cross-reactivity is unlikely between sulfo

Successful treatment with mepolizumab in a case of allergic bronchopulmonary aspergillosis complicated with nontuberculous mycobacterial infection. Authors: Tsubouchi H1, Tsuchida S1, Yanagi S1, Shigekusa T1, Miura M2, Sakaguchi K2, Matsumoto N1, Nakazato M1. Author information 1 Division of Neurology, Respirology, Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, Kiyotake, Japan. 2 Kyoritsu Clinic, Miyakonojo, Japan. Abstract Allergic bronchopulmonary aspergillosis (ABPA) is a complex hypersensitivity reaction that is associated with an allergic immunological response to Aspergillus species via Th2-related inflammation. The long-term use of a systemic corticosteroid is often needed for the treatment of ABPA. However, systemic corticosteroid treatment imposes a risk of the onset of a nontuberculous mycobacterial infection. Here we report the case of a patient with ABPA who required the long-term use of an oral cortic

Anisakis Nematodes in Fish and Shellfish- from infection to allergies. Authors: Aibinu IE1, Smooker PM1, Lopata AL2,3,4. Author information 1 School of Science, Discipline of Biosciences and Food Technology, Royal Melbourne Institute of Technology (RMIT) University, Bundoora, Victoria, Australia. 2 Molecular Allergy Research Laboratory, Department of Molecular and Cell Biology, James Cook University, Townsville, Queensland, Australia. 3 Australian Institute of Tropical Health and Medicine, James Cook University, Townsville, Queensland, Australia. 4 College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, Queensland, Australia. Abstract Anisakidosis is a zoonotic parasitosis induced by members of the family Anisakidae. The anisakid genera includes Anisakis, Pseudoterranova, Hysterothylacium and Contracaecum. The final definitive hosts of these nematodes are marine mammals with a complex life cycle. These nematode parasites use different

Nasal IgE production in allergic rhinitis: Impact of rhinovirus infection. Authors: Hamed A1, Preston DC1, Eschenbacher W1, Khokhar D1, Workman L1, Steinke JW1, Heymann P2, Lawrence M1, Soto-Quiros M3, Platts-Mills TAE1,4, Payne S1,5, Borish L1,4. Author information 1 Department of Medicine, University of Virginia Health System, Charlottesville, Virginia. 2 Department of Pediatrics, University of Virginia Health System, Charlottesville, Virginia. 3 Hospital Naçional de Niños, San José, Costa Rica. 4 Department of Microbiology, University of Virginia Health System, Charlottesville, Virginia. 5 Department of Otolaryngology, University of Virginia Health System, Charlottesville, Virginia. Abstract BACKGROUND: Rhinovirus (RV) infections exacerbate asthma in part by enhancing an allergic state, and these exacerbations can be mitigated via administration of anti-IgE. OBJECTIVE: We investigated the presence of local IgE production in the nose of allergic and non-allergic

Eosinophilic colitis and colonic eosinophilia. 　 Authors: Walker MM1, Potter MD, Talley NJ. 1Faculty of Health and Medicine, School of Medicine & Public Health, University of Newcastle, Callaghan, Australia. Abstract PURPOSE OF REVIEW:   Eosinophilic colitis is a rare condition, with a prevalence rate in the USA of 2-3/100  000 persons (0.003%), but diagnosed in 0.1% of biopsies in those colonoscoped for diarrhoea. Secondary colonic eosinophilia is more common and associated with systemic, colonic and infectious diseases. In this review, the latest advances in diagnosis, treatment and prognosis are summarized and discussed.   RECENT FINDINGS:   What constitutes a 'normal' count of eosinophils is poorly documented but there are recent studies that establish normal colonic eosinophil ranges as well as distinguishing histological and clinical findings in primary eosinophilic colitis and secondary colonic eosinophilia in children and adults. Primary eosinop

Urticaria in children and adolescents: An updated review of the pathogenesis and management. 　 Authors: Kudryavtseva AV1, Neskorodova KA1, Staubach P2. 1I.M. Sechenov First Moscow State Medical University, Moscow, Russia. 2Department of Dermatology, University Medical Center, Mainz, Germany. Abstract The present survey represents the latest data on diagnosis and management of childhood urticaria. It has been observed that urticaria occurs less often in children than adults, with symptoms rarely lasting for over 6 weeks. Triggers or aggravating factors can be found only in 21%-55% of cases. Finding autoantibodies in children does not impact a disease prognosis, unlike in adult patients, where the presence of autoantibodies is associated with a more prolonged run of the disease, a more severe prognosis and more intensive treatment methods. The incidence of food allergy equals to 8%-10% of cases. The incidence of Helicobacter Pylori infection in children is lower than that in

Vaccine-associated hypersensitivity. Authors: McNeil MM1, DeStefano F2. 1Immunization Safety Office, Centers for Disease Control and Prevention, Atlanta, Ga. Electronic address: mmm2@cdc.gov.2Immunization Safety Office, Centers for Disease Control and Prevention, Atlanta, Ga. Abstract Vaccine-associated hypersensitivity reactions are not infrequent; however, serious acute-onset, presumably IgE-mediated or IgG and complement-mediated anaphylactic or serious delayed-onset T cell-mediated systemic reactions are considered extremely rare. Hypersensitivity can occur because of either the active vaccine component (antigen) or one of the other components. Postvaccination acute-onset hypersensitivity reactions include self-limited localized adverse events and, rarely, systemic reactions ranging from urticaria/angioedema to full-blown anaphylaxis with multisystem involvement. Risk of anaphylaxis after all vaccines is estimated to be 1.31 (95% CI, 0.90-1.84) per million vaccine doses