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Frey’s syndrome in the allergology consultation
Síndrome Frey en la consulta de alergología
July Andrea Ospina-Cantillo 1 Ruth Helena Ramírez-Giraldo1 Iris Yansa Castelblanco-Arango 1 Ricardo Cardona1
1Universidad de Antioquia, Grupo de Alergología Clínica y Experimental
Correspondencia: Ricardo Cardona. rcv2016udea@gmail.com Medellín, Colombia
Abstract
Background: Frey’s syndrome is a group of symptoms that include unilateral sweating with
malar region and external ear reddening after eating or drinking some food. It is a lesion of the
auriculotemporal nerve that is secondary to surgery, parotid gland infection or facial trauma.
Clinical cases: Three children between 4 and two and a half years of age: two girls and one boy.
They had self-limiting unilateral erythematous facial macules that reached the external ear, without
rash, itching, angioedema and gastrointestinal or respiratory symptoms; its onset was associated
with the consumption of acid and some sweet foods. Symptom reproduction of was observed in
the path of the auriculotemporal nerve. Their histories included cesarean section delivery owing to
cephalopelvic disproportion (case 1), birth by operative vaginal delivery with forceps (case 2) and
cesarean delivery owing to preeclampsia (case 3).
Conclusions: Frey’s syndrome is often mistaken with food allergy, leading to unnecessary dietary
restrictions. Sweating is often absent in children owing to possible eccrine glands immaturity.
Keywords: Frey’s syndrome; Auriculotemporal nerve; Gustatory flushing
Este artículo debe citarse como: Ospina-Cantillo JA, Ramírez-Giraldo RH, Castelblanco-Arango IY, Cardona R.
Síndrome Frey en la consulta de alergología. Rev Alerg Mex. 2018;63(3):220-224
Texto completo: DOI: 10.29262/ram.v65i3.332
ORCID:
July Andrea Ospina-Cantillo, 0000-0003-3828-2456
Ruth Helena Ramírez-Giraldo, 0000-0003-2232-8114
Iris Yansa Castelblanco-Arango, 0000-0002-7231-6528
Ricardo Cardona, 0000-0002-7428-2413
Iris Yansa Castelblanco-Arango, 0000-0002-7231-6528
Ricardo Cardona, 0000-0002-7428-2413
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