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Inhaled Combined Budesonide-Formoterol as Needed in Mild Asthma. Fecha: Viernes 31 de mayo

Inhaled Combined Budesonide-Formoterol as Needed in Mild Asthma Authors:  O'Byrne PM1, FitzGerald JM1, Bateman ED1, Barnes PJ1, Zhong N1, Keen C1, Jorup C1, Lamarca R1, Ivanov S1, Reddel HK1. 1 From the Firestone Institute for Respiratory Health, St. Joseph's Healthcare and Department of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON (P.M.O.), and the Institute for Heart and Lung Health, University of British Columbia, Vancouver (J.M.F.) - both in Canada; the Division of Pulmonology, Department of Medicine, University of Cape Town, Cape Town, South Africa (E.D.B.); Airway Disease Section, National Heart and Lung Institute, Imperial College, London (P.J.B.); State Key Laboratory of Respiratory Diseases, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China (N.Z.); AstraZeneca Research and Development, Gothenburg, Sweden (C.K., C.J., S.I.); AstraZeneca Research and Development, Barcelona (R.L.); and Woolcock Institu...

IL-24 is a common and specific autoantigen of IgE in patients with chronic spontaneous urticaria. Fecha: Miércoles 29 de mayo

IL-24 is a common and specific autoantigen of IgE in patients with chronic spontaneous urticaria Authors:   Schmetzer O1, Lakin E2, Topal FA2, Preusse P2, Freier D2, Church MK2, Maurer M2. 1 Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin, Germany. Electronic address: oliver.schmetzer@charite.de. 2 Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin, Germany. Abstract: BACKGROUND: The efficacy of omalizumab (anti-IgE) and increased IgE levels in patients with chronic spontaneous urticaria (CSU) suggest autoallergic mechanisms. OBJECTIVE: We sought to identify autoallergic targets of IgE in patients with CSU. METHODS: Serum samples of patients with CSU together with those of patients with idiopathic anaphylaxis and healthy control subjects (7 of each) were screened for IgE autoantibodies by using an array of more than 9000 proteins. Sera of 1062 patients with CSU and 482 healthy control subjects were...

2019 ARIA Care pathways for allergen immunotherapy. Fecha: Martes 28 de mayo

2019 ARIA Care pathways for allergen immunotherapy. Authors:  Bousquet J1,2, Pfaar O3, Togias A4, Schünemann HJ5, Ansotegui I6, Papadopoulos NG7, Tsiligianni I8, Agache I9, Anto JM10,11,12,13, Bachert C14, Bedbrook A1, Bergmann KC15, Bosnic-Anticevich S16, Bosse I17, Brozek J5, Calderon M18, Canonica GW19, Caraballo L20, Cardona V21, Casale T22, Cecchi L23, Chu DK5, Costa E24, Cruz AA25, Czarlewski W26, Durham SR27, Du Toit G26, Dykewicz M28, Ebisawa M29, Fauquert JL30, Fernandez-Rivas M31, Fokkens WJ32, Fonseca J33, Fontaine JF34, van Wijk RG35, Haahtela T36, Halken S37, Hellings PW38, Ierodiakonou D8, Iinuma T39, Ivancevich JC40, Jacobsen L41, Jutel M42, Kaidashev I43, Khaitov M44, Kalayci O45, Kleine Tebbe J46, Klimek L46, Kowalski ML47, Kuna P48, Kvedariene V49, La Grutta S50, Larenas-Linemann D51, Lau S52, Laune D53, Le L54, Carlsen KL55, Lourenço O56, Malling HJ57, Marien G58, Menditto E59, Mercier G60, Mullol J61, Muraro A62, O'Hehir R63, Okamoto Y39, Pajno GB64, Park...

Timing of Food Introduction and the Risk of Food Allergy. Fecha: Lunes 27 de mayo

Timing of Food Introduction and the Risk of Food Allergy Authors:   Ferraro V1, Zanconato S2, Carraro S3. 1 Women's and Children's Health Department, University of Padova, via Giustiniani 2, 35128 Padova, Italy. ferrarovalentina@hotmail.com. 2 Women's and Children's Health Department, University of Padova, via Giustiniani 2, 35128 Padova, Italy. stefania.zanconato@aopd.veneto.it. 3 Women's and Children's Health Department, University of Padova, via Giustiniani 2, 35128 Padova, Italy. silvia.carraro@unipd.it. Abstract: Given that the prevalence of pediatric IgE-mediated food allergies (FA) has followed a substantive increase in recent decades, nowadays, a research challenge is to establish whether the weaning strategy can have a role in FA prevention. In recent decades, several studies have demonstrated that delayed exposure to allergenic foods did not reduce the risk of FA, leading to the publication of recent guidelines which recommend against dela...

Fisiopatología de la alergia a hongos

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Fisiopatología de la alergia a hongos (Dra. Gloria Gil)

Alergología a cuatro manos: dermatitis atópica

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Alergología a cuatro manos: dermatitis atópica por Dra. Gloria Gil y Dr. Ricardo Cardona

Atopic eczema and major cardiovascular outcomes: A systematic review and meta-analysis of population-based studies. Fecha: Viernes 24 de mayo

Atopic eczema and major cardiovascular outcomes: A systematic review and meta-analysis of population-based studies. Authors:  Ascott A1, Mulick A2, Yu AM3, Prieto-Merino D2, Schmidt M4, Abuabara K5, Smeeth L2, Roberts A6, Langan SM2. 1 Royal Sussex County Hospital, Eastern Road, Brighton, United Kingdom. Electronic address: annaascott@doctors.org.uk. 2 Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom. 3 Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada. 4 Department of Clinical Epidemiology, Aarhus University Hospital, Denmark Department of Cardiology, Regional Hospital West Jutland, Herning, Denmark. 5 Program for Clinical Research, Department of Dermatology, University of California, San Francisco School of Medicine, San Francisco, Calif. 6 Nottingham Support Group for Carers of Children with Eczema, Nottingham, United Kingdom. Abstract:  BACKGROUND: Atopic eczema is ...